What is the effect of Lp(a) on plaque? 

Growing evidence is linking Lp(a) to the presence of plaque, but the association is not always straightforward, as demonstrated by presentations at ACC.25. In a sub analysis of data from the GLOBAL study of cardiac CT in suspected coronary artery disease (CAD), Lp(a) was associated with the presence of plaque, especially high risk, partially calcified plaque (PCP), independently of apoB.¹