Until recent years, Lp(a) has lagged behind other atherogenic lipoproteins in the development of targeted lipid lowering therapies. That is now changing, as Professor Ioanna Gouni-Berthold, University of Cologne, Germany explains.
Professor Steve Nissen, Cleveland Clinic Foundation, Ohio, USA, reports data from a single ascending dose study investigating the safety and Lp(a) lowering effects of lepodisiran in patients without cardiovascular disease but with Lp(a) levels ≥75 nmol/L (≥30 mg/dL).
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