
Pre-eclampsia (PE), foetal growth restriction, gestational hypertension and premature delivery all appear to be more common in women with raised Lp(a) in the first trimester of pregnancy. In a prospective study of 150 pregnant women at less than 12 weeks of foetal gestation with no history of PE, 64.7% of participants with Lp(a) ≥30 mg/dL developed PE compared to 15.5% of those with lower Lp(a).