Lp(a) is among the serum lipoproteins that are significantly increased in patients with pre-eclampsia. Samples taken during the Child Health Advances from Research with Mothers (CHARM) study at 89 and 189 gestational days showed significantly higher levels of direct LDL-C (+ 10%), small dense LDL-C (+ 18%), apoB (+ 10%), and Lp(a) (+ 50%) in women with pre-eclampsia compared to healthy controls (Table).