Professor Gilles Lambert
Disclosure details
None.Université de La Réunion, Laboratoire Inserm UMR1188 DéTROI
77 Avenue du Dr JM Dambreville – 97410 Saint Pierre (France)
Gilles Lambert is Professor in Cell Biology and Biochemistry at the University of La Réunion Medical School (France) and a group leader at Inserm UMR1188 DéTROI laboratory.
Professor Lambert was awarded a PhD in Pathophysiology from the University of Paris in 1998. He specialized in lipidology, first as a post-doctoral fellow at the Molecular Disease Branch of the National Institutes of Health (Bethesda MD, USA) under the supervision of Dr. H Bryan Brewer Jr. and then as a senior research fellow at the Heart Research Institute (Sydney NSW, Australia) in the lipid research group led by Professor Kerry-Anne Rye.
In recent years, Professor Lambert has conducted seminal research projects on PCSK9, a protein that targets the LDL receptor for intracellular degradation, and the target of novel cholesterol lowering therapies: the PCSK9 inhibitors. A major aim of his research is to identify the cellular pathways by which PCSK9 modulates the circulating levels of lipoprotein (a), a highly atherogenic lipoprotein species. His current research goals are to elucidate the genetic and the metabolic determinants of elevated lipoprotein (a) and associated cardiovascular disease risk.
